Semaglutide – A Game Changer in Obesity Treatment

Semaglutide - A Game-Changer in Obesity Treatment

A unique and promising treatment has emerged in the ever-evolving domain of weight loss treatments – Semaglutide. With its recent approval by the U.S. Food and Drug Administration in 2021, this injectable medication, initially designed for diabetes management, has taken the medical and aesthetic world by storm. Now, it is carving a niche as a ground-breaking approach to chronic weight management, garnering attention from health professionals and individuals seeking effective solutions.

Semaglutide’s effectiveness in promoting weight loss has been consistently demonstrated through research and clinical trials. This medication highlights the importance of viewing obesity as a chronic metabolic disease, shifting the perspective from merely relying on willpower and lifestyle changes to a medical approach.

Embracing the optimism that surrounds this new treatment, SkinFx Med Spa is determined to provide clients with access to innovative options that align with their weight loss journey.

However, as with any medical intervention, it’s essential to recognize that Semaglutide has many intricacies. While we celebrate its potential as a transformative agent, SkinFx Med Spa is committed to approaching every client’s needs with individualized care and attention. Understanding Semaglutide’s benefits and limitations enables us to make informed decisions together, empowering you on your path to wellness.


In this article, we will look closer at Semaglutide for weight loss, delving into its mechanisms, effects, and remarkable progress in the fight against obesity. As you embark on this informative journey with us, we aim to provide you with a clear and optimistic perspective on the potential of semaglutide to become a powerful ally in your quest for a healthier and happier life.


1. What is Semaglutide and How Does it Work For Work Weight Loss?

Semaglutide lies in the category of medications known as glucagon-like peptide-1 receptor agonists, abbreviated as GLP-1 RAs. It works by imitating the actions of the GLP-1 hormone, which is naturally released in the gastrointestinal tract after meals. 

Semaglutide was initially designed as a treatment for Type 2 diabetes, assisting the body in producing more insulin. Thereby reducing blood sugar levels. Over the past 15 years, it has been prescribed for diabetes management with significant success.

However, the beneficial effects of GLP-1 do not end there. Higher levels of this hormone also interact with specific brain regions responsible for suppressing appetite and signaling feelings of fullness. This dual-action property has led to the use of Semaglutide, combined with diet and exercise, for significant weight loss in individuals who are obese.

In addition to its potential for weight management, Semaglutide usage has been associated with a decreased risk of cancer, diabetes, and heart disease. This makes it a promising option for those seeking wide-ranging health benefits while tackling weight-related concerns.


1.1 Who can use Semaglutide for weight loss? 

Semaglutide for weight loss is approved for use in specific groups of personages based on their age, body mass index (BMI), and certain health conditions. The medication can be prescribed for adults and adolescents aged 12 years and older.

In adults, Semaglutide (Wegovy) is specified for long-term weight management in two categories:

  • Adults who are obese, with a BMI, i.e. Body Mass Index of 30 kg/m2 or higher.
    • Semaglutide treatment is suitable for adults who are considered obese and have weight-related conditions if they have a Body mass index (BMI) of 27 kg/m2 or higher and are suffering from at least one weight-related health condition, such as high cholesterol levels, type 2 diabetes, high blood pressure, etc.
  • Semaglutide can be used by teenagers aged 12 years and older if they have an initial BMI at or above the 95th percentile for their sex and age based on growth charts.

It is pertinent to note that Semaglutide is used as an aide to diet and exercise for weight management. Other brand names of prescription drugs that contain Semaglutide, such as Ozempic (injection) or Rybelsus (oral tablets), are mainly approved for treating type 2 diabetes and can also lead to weight loss. However, they are not explicitly designated for weight loss.


2. How Long Does it Take for Semaglutide To Work?

Semaglutide typically takes some time to show its full effect on weight loss. While you may begin to see some initial weight loss within the first four weeks of treatment, the significant and sustained results may take several months.

When starting Semaglutide treatment, your provider will often initiate with a lower dose and gradually increase it over time. This approach helps to minimize potential side effects in the gastrointestinal tract, such as nausea and diarrhea. It generally takes around 17 weeks to reach the final maintenance dose of Semaglutide.

Results from studies conducted by the manufacturer for 68 weeks demonstrated that, on average, adults using Semaglutide lost approximately 35 lbs (15.9 kg), which accounts for about 15% of their body weight. In contrast, those who received a placebo (inactive treatment) lost about 6 lbs (2.7 kg), or roughly 2.5% of their body weight.

For children aged 12 years and older, Semaglutide also showed promising results. After 68 weeks of treatment, their body mass index (BMI) decreased by 16.1% compared to a 0.6% reduction in the placebo group. Moreover, 77% of children receiving Semaglutide experienced a decrease in BMI of at least 5%, whereas only 20% of those on the placebo achieved a similar outcome.

It’s essential to remember that individual responses to Semaglutide may vary. While some individuals may experience rapid weight loss, others may see more gradual progress over time. As with any weight loss treatment, it’s crucial to adhere to the prescribed dosage and follow your healthcare provider’s guidance to achieve the best possible results.


3. Who Should Avoid Semaglutide? 

Individuals with certain medical conditions should avoid Semaglutide due to potential risks and complications. Semaglutide should be avoided if you have any of the following medical issues:

Medullary Thyroid Cancer: Medullary thyroid cancer is a type of thyroid cancer caused by the thyroid gland’s C cells. Semaglutide can increase the growth of these cells, so if you have a history of medullary thyroid cancer or a family history of this condition, you should not use Semaglutide.

History of Gallbladder Disease: Semaglutide can increase the risk of gallbladder issues, including gallstones.

 If you have a history of gallbladder disease or are at risk of developing it, your provider will advise against using Semaglutide.

History of Pancreatitis: Pancreatitis is the inflammation of the pancreas, and Semaglutide can intensify the risk of this condition. If you have a history of pancreatitis or are at risk of developing it, Semaglutide may not suit you.

Multiple Endocrine Neoplasia Syndrome Type 2 (MEN2): MEN2 is a genetic disorder causing certain tumors, including medullary thyroid cancer. As Semaglutide can worsen this condition, individuals with MEN2 should avoid using Semaglutide.

If you have any of these medical issues or are unsure about your eligibility for Semaglutide treatment, discussing your medical history with a qualified healthcare professional is crucial. They will examine your health and guide you on the most suitable and safe weight management options.


3.1 What Special Precautions Should I Follow Before Semaglutide Treatment? 

· Inform your provider about allergies to Semaglutide or other GLP-1 receptor agonists.

· Provide a complete list of all medicines, vitamins, and supplements you take to your provider.

· Share your history of pancreatitis, diabetic retinopathy, gallbladder disease, or kidney disease with your provider.

· Discuss plans for pregnancy or breastfeeding with your provider.

· Inform your Provider about significant changes in diet, exercise, weight, and any illness or stress.


4. What are the Potential Side Effects of Semaglutide?

More common:

  • Diarrhea

Less common:

  • Constipation
  • Hair loss


 Change in taste, Loss of taste, Bleeding, blistering, burning, coldness, discoloration of the skin, warmth, redness, swelling, tenderness, soreness, stinging, itching, rash, numbness, tingling, lumps, scarring, infection, inflammation, hives, or a feeling of pressure.

In a Nutshell:

All in all, Semaglutide offers a promising avenue for weight management, providing hope for individuals struggling with obesity or overweight. As a GLP-1 receptor agonist, it shows efficacy in both diabetes management and significant weight loss. 

However, precautions must be exercised, considering its contraindications for individuals with specific health conditions. Before embarking on Semaglutide treatment, it is crucial to consult a healthcare professional to ensure its safe and appropriate use. With careful monitoring and personalized care, Semaglutide presents a potential transformative option in the ongoing quest for improved overall health and sustainable weight loss management.

If you’re ready to take the next step on your health journey, Book Your Appointment with us.

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